The commune of Chambolle-Musigny lies just north of Vougeot and south of Morey-Saint-Denis on two steep slopes at either end of the commune which rise above the village of Chambolle in the valley between them. Its vineyards occupy 423 acres, 223 of which produce Chambolle's village wines, and an additional 150 acres divided among 24 premiers crus. The remaining 40 acres are in the commune's two grands crus: Le Musigny, at the southern extremity, and Bonnes-Mares, at the northern extremity, a small part of which spills into Morey-Saint-Denis.
Chambolle-Musigny is unique in the Côte de Nuits for the chalky composition of its soils (unlike the clay soils relevant elsewhere). The thin, calcareous layer clings to a hard rocky soil beneath, which stresses the vines and sharply restricts their yield; village and premier cru production is less than 15 hectolitres (5,625 gallons) per hectare, one-third of the legal maximum. But these soils are responsible for Chambolle-Musigny's exceptional delicacy and a character possessed by no other wine of the Côte de Nuits.